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ARC PD in real-time live cell assay technologies

Our UWA node is now currently recruiting for an ARC Postdoctoral Fellow who will participate in the research program of the ARC Centre for Personalised Therapeutics Technologies within the Faculty of Health and Medical Sciences at the Harry Perkins Institute of Medical Research.

The Postdoctoral Fellow will manage the day-to-day running of the Centre for Personalised Therapeutics Technologies project entitled ‘Development and utilisation of real-time live cell assay technologies and complementary diagnostics to improve profiling of therapeutics’.

For further information download the UWA CPTT ICPD Position Description

Applications close 18th October 2018.

Accelerating Australia National Conference – Nov 27th in Adelaide

The Accelerating Australia National Conference is being held alongside the ASCEPT Scientific Meeting in Adelaide.

Register for this one day Accelerating Australia event with keynote from Daria Mochly-Rosen, Founder and Co-director of Stanford SPARK.

See the Accelerating Australia Conference Flyer for further information.

Note: if you are going to ASCEPT you  can attend this one day event for free as part of your ASCEPT registration.

Funding success for CI Alice Pebay

Congratulations to University of Melbourne researcher and ARC CPTT Chief Investigator A/ Professor Alice Pèbay who has recently been awarded a highly competitive NHMRC Research Fellowship.

Her project “Human induced pluripotent stem cells to understand neurodegeneration” will use stem cells taken from patients to generate unique and important eye tissue models relevant in certain eye diseases (glaucoma, age-related macular degeneration) and the brain (Alzheimer’s disease). These models will allow us to study these diseases in extreme detail. The program will help to uncover how and why these diseases develop and will be used to search for new treatments to prevent them or to slow their progression.

The NHMRC funding supports research across the full spectrum of health and medical research, from basic science through to clinical, public health and health services research.


International Visit – Dr Jon Koff

The Centre’s Melbourne University node recently hosted a 7 week visit by Associate Professor Jon Koff of Yale Medical School, who was with us in Australia for his sabbatical.

Jon has brought with him an array of interests and expertise (Asthma; Bronchiectasis; Cystic Fibrosis; Influenza, Human; Lung; Viruses; Respiratory Mucosa) that has been a wonderful addition to our weekly lab meeting discussions.

In 2011, Dr. Koff joined the faculty at Yale University to direct the Adult CF Program. His laboratory focuses on pulmonary innate immune responses to pathogens in chronic obstructive lung diseases and lung injury. His postdoctoral studies led to a research program that implicated EGFR inhibition as a potential therapeutic target for respiratory viral infection (e.g., Influenza, Rhinovirus, RSV), which has important implications for chronic obstructive lung diseases that have increased airway epithelial EGFR signaling, and evidence for increased susceptibility to viral infections. This has led to translational research in virus-induced asthma exacerbations. He also uses in vivo and in vitro models to investigate innate immune responses to post-viral bacterial infections with a focus on signaling pathways that regulate host tolerance during lung injury.

While he was here, Jon presented his work on “Epidermal Growth Factor Receptor Regulation of Interferons: Implications in Lung Inflammation and Asthma” to the Department of Pharmacology (pictured below to the left with Centre Director, Professor Alastair Stewart). Many thanks to Jon visiting us and sharing his wealth of experience with the whole team.


ARC PD in microfluidics

We are currently recruiting for an ARC Postdoctoral Fellow who will participate in the research program of the ARC Centre for Personalised Therapeutics Technologies within the Department of Pharmacology and Therapeutics at the University of Melbourne.

The Postdoctoral Fellow will carry out research projects aligned with the Centre in the area of microfluidics. The Postdoctoral Fellow will be responsible for development and the design, collection and analysis of project data. The Postdoctoral Fellow will also be responsible for writing scientific reports and manuscripts, coordinating research activities, participating in the characterisation of research directions and any other research activities as required. This role has a strong translational focus with links to industry.

For further information download the Position Description and Selection Criteria

Applications close 16th September 2018.


New ARC Training Centre for CI Peter Lee

We are very pleased to congratulate Professor Peter Lee and colleagues including A/Professor Andrea O’Connor, both CIs on the ARC CPTT, who have been successful in their bid for a Training Centre for Medical Implant Technologies.

The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, international collaborations and a generation of industry-ready researchers critical for growing Australia’s industry. The advances in materials and savings in time for procedures will reduce costs.

Congratulations Peter, Andrea and team.


Media Release – New Partnership to Accelerate Therapeutic Technology

Today the Australian Mathematical Sciences Institute’s (AMSI) put out a media release regarding our partnership with them through their APR.Intern program.

Enhancing APR.Intern’s focus on accelerating women into STEM, the collaboration will increase PhD industry engagement through placement of 24 of the Centre’s skilled PhDs in short-term research projects over four years.

AMSI Director Professor Geoff Prince said the partnership would open exciting opportunities to address gender equity while equipping a new generation of medical research leaders.

“These projects will have transformative impacts for health innovation, while training PhDs with essential skills to drive commercial medical research and development,” he said.

With over 500 Australian MedTech companies already in operation and skill demand growing, the ARC CPTT aims to foster supply of PhDs with both the research and industry skills to drive product research and development, and oversee regulatory affairs which are required for future growth of the sector.

ARC Centre for Personalised Therapeutics Technologies Director, Professor Alastair Stewart said facilitation of PhD industry engagement opportunities was central to meeting this challenge in Australia.

“A core mission for our Centre and APR.Intern, this partnership opens critical avenues to provide PhDs with essential experiential industry training helping to future proof the biomedical workforce,” says Professor Stewart.

See the full details here: Media Release_AMSI 23 July 2018

In the Media – “Breathing Easy”

Professor Alastair Stewart, Director of the Centre for Personalised Therapeutics Technologies (CPTT) has been featured on Pursuit, the University of Melbourne’s content platform.

The article, breathing easy, highlights research conducted in the Stewart lab on the molecular cause of steroid resistance in the lungs and how this critical problem for severe asthmatics now has a new inhaled treatment on the way…

PhD Scholarship Opportunities

PhD Opportunities with the ARC Centre for Personalised Therapeutics Technologies

We are currently seeking outstanding applicants for multiple PhD scholarship opportunities associated with ARC Centre for Personalised Therapeutics Technologies in the Department of Pharmacology and Therapeutics at The University of Melbourne.

The ARC Industry Transformation Training Centre is a 5-year National/International collaboration with nodes at Monash University and University of Western Australia. The Centre has 15 Industry based partners, is strongly aligned to the goals of industry growth sector body, MTPConnect, and collaborates with Accelerate Australia in experiential entrepreneurship training and mentorship.

The Centre aims to develop breakthrough enabling technology for new industrial applications of organ-on-a-chip technology, including the use of 3D bioprinting technologies across three themes: PhD students will research the use and development of microfluidics environments; real-time cell/organoid assay technologies, and/or bioprinting to generate novel tools for lead qualification in therapeutic discovery. The selected PhD candidates will be co-supervised by Industry and University based supervisors (Prof Alastair Stewart / A/Prof Alice Pebay) and will participate in an entrepreneurship-focussed training programme running in parallel to the PhD research. This programme will cover intellectual property, project management, regulatory environments, innovation, funding models and will include access to highly qualified industry-based mentors.

A tax-free scholarship of AU$31,828 is available to successful candidates for 3 years, with potential for a single extension of 6-months. It is a condition of the scholarship that the successful applicant completes a minimum of 12-month placement with an ARC CPTT industry partner during and as part of their candidature.  Selected applicants may be eligible and encouraged to apply for alternative competitive scholarships.

Applicants must meet the eligibility criteria for enrolment in Doctor of Philosophy (PhD), including the required level of English language proficiency.  In addition, a high level of interpersonal skill level is required for this demanding and highly privileged opportunity.

Expressions of interest are invited from applicants with an appropriate background, until the end of 2018 (or until filled).

Selection Criteria

  • Academic merit and CV;
  • Area of study and research proposal;
  • Academic referee reports;
  • Interest in and/or experience working with industry partners;
  • Evidence of well-developed interpersonal and written communication skills.

For more information please contact Centre Manager, Dr Narelle Tunstall

The ARC CPTT is funded by the Australian Government through the ARC Industrial Transformation Research Program.