📣 We are excited to announce the publication of our latest research, “Dual-Purpose Aptamer-Based Sensors for Real-Time, Multiplexable Monitoring of Metabolites in Cell Culture Media” in ACS Nano by ACS Publications.
This study introduces a novel biosensor that enables real-time measurement of nutrient and pH levels in cell culture. This innovation underscores the ARC CPTT’s commitment to advancing the use of non-animal methods for drug testing.
With the development of more complex in vitro systems to replace or complement animal models, there is a growing need for real-time monitoring of cell culture conditions in both biomedical research and industrial settings. Using innovative technology, our team has created a miniature, easy-to-use biosensor that can quickly and accurately measure specific nutrient concentrations and pH levels in the culture medium.
Continuous monitoring helps maintain optimal conditions to keep cells healthy throughout experiments by better emulating physiological conditions found in the human body. The biosensor can also be used to assess how drugs affect cell metabolism and induce toxicity which will help accurately predict the effectiveness of drugs in clinical trials.
Curious to learn more? Check out the full article here.
Congratulations to ARC CPTT PhD student Yiling (Iris) Yang and CPTT members Bryan Gao, Bryce Widdicombe, Xiaodan Zhang, Jana Zielinski, Tianhong (Tina) cheng, Avanka Gunatilaka, Dr. Ranjith R Unnithan and Alastair Stewart at The University of Melbourne together with our collaborators Kaylyn K. Leung and Kevin Plaxco at The University of California, Santa Barbara.
